HIPPOCAMPAL ORNITHINE DECARBOXYLASE/SPERMIDINE PATHWAY MEDIATES H2S-ALLEVIATED COGNITIVE IMPAIRMENT IN DIABETIC RATS: INVOLVING ENHANCMENT OF HIPPOCAMPAL AUTOPHAGIC FLUX

Hippocampal ornithine decarboxylase/spermidine pathway mediates H2S-alleviated cognitive impairment in diabetic rats: Involving enhancment of hippocampal autophagic flux

Introduction: We have previously demonstrated the antagonistic role of hydrogen sulfide (H2S) in the cognitive dysfunction of streptozotocin (STZ)-induced diabetic rats.It has been confirmed that the impaired hippocampal autophagic flux has a key role in the pathogenesis of cognitive impairment and that ornithine decarboxylase (ODC)/spermidine (Spd

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Temporal dynamics of attentional selection in adult male carriers of the fragile X premutation allele and adult controls

Carriers of the fragile X premutation allele (fXPCs) have an expanded CGG trinucleotide repeat size within the emph{FMR1} gene and are at increased risk of developing Fragile X-associated Tremor Ataxia Syndrome (FXTAS).Previous research has shown that male Mirror Brackets and Accessories (Universal) fXPCs with FXTAS exhibit cognitive decline, predo

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